NAD nasal spray compared: Arc-1 prescription spray at $149.99 vs Real Peptides 1000mg research spray at $120, plus vial and injection prices and evidence.
Independently ranked by quality, purity and value.
Compounded NAD+ nasal spray from a telehealth platform. Needle-free delivery with physician oversight.
NAD+ in a 1000 mg liquid spray format. Lab tested per lot with COA published. Ships from US stock.
NAD+ research peptide in a multi-dose vial. Independent lab tested with COA published per lot. Ships from US stock.
Physician-guided NAD+ injection kit from a licensed telehealth platform. Includes online consultation.
Order online; most orders arrive in a few days in discreet packaging.
Every pick has a batch-matched certificate of analysis we can read.
We check that real potency matches what the label promises.
Simple, transparent formulas — no mystery fillers or additives.
Scored on real cost per serving, not just sticker price.
Every guide is reviewed by at least one member of this panel before publication.
Science journalist who fact-checks every claim against primary literature and ensures our guides stay accurate after each update.
Tracks peptide vendor sourcing, cold-chain logistics and batch-matching practices to verify supply-chain integrity.
PhD in molecular pharmacology. Evaluates the published animal and clinical data behind every peptide we cover.
Analytical chemist who audits third-party certificates of analysis for potency, residual solvents and heavy-metal contamination.
A prescription NAD nasal spray from the telehealth service Arc-1 is listed at $149.99, while Real Peptides sells a 1000mg NAD+ liquid spray for $120.00, which works out to $0.12 per mg of listed content. Those two numbers look close. The products behind them are not. One comes with a physician intake and a pharmacy-compounded product, and the other is a research chemical sold with a lab certificate and a "not for human consumption" label.
As a person making career comparisons between sellers, certificates of analysis and costs of products that we buy, I created this website because NAD nasal spray mixes both two markets on results page. Below you can find out a brief summary of every option along with its price and the information concerning putting NAD+ into your nose.
We keep track of four NAD+ listings originating from two different sources, which can be categorized into two groups: prescription and research-grade. Arc-1 uses a telehealth model, meaning that a doctor must approve you beforehand to obtain NAD+. Real Peptides can supply research-grade compounds with a valid third-party COA and no doctor’s consultation required.
| Product | Vendor | Listed price | Format | Access |
|---|---|---|---|---|
| NAD+ Nasal Spray | Arc-1 | $149.99 | Compounded nasal spray | Telehealth intake + prescription |
| NAD+ Injections | Arc-1 | $299.99 | Compounded injectable | Telehealth intake + prescription |
| NAD+ Peptide Liquid Spray (1000mg) | Real Peptides | $120.00 | Liquid spray | Research use only |
| NAD+ Peptide (Multi-Dose Vial) | Real Peptides | $60.00 | Lyophilized powder | Research use only |
The cheapest item on the list is the research vial at $60.00, and the most expensive is the prescription injectable at $299.99. The full lineup, with specs, sits on the products page.
The Arc-1 spray is a product that requires a prescription, while Real Peptides spray belongs to the category of research compounds. The difference between the two sprays is more important than the price difference of $29.99 between them.
With Arc-1, you complete an online medical intake, a physician reviews it, and if a prescription is written, a compounding pharmacy makes the spray and it ships direct to your door. Arc-1 runs it on a monthly subscription model and offers 30-day returns. The prescriber, not a website, decides whether it suits you.
Real Peptides sells its spray labelled for research use only. There is no doctor in the loop and no medical guidance comes with it. What you do get is a third-party COA, US stock and free US shipping on orders over $250. Buyers sometimes treat the two as interchangeable because both say "NAD+ spray" on the box. They are sold under completely different rules, and our page on whether a prescription is needed goes through that line in detail.
The nasal route is needle-free, and that is the only advantage that is firmly established. Whether a meaningful amount of NAD+ reaches circulation through the nose is a separate question, and Arc-1's own listing notes that bioavailability data for the nasal route are limited.
NAD+ is a coenzyme that exists in various types of cells and plays an important role in energy metabolism. It has been known that our NAD+ levels drop as we get older but any claim which states that using an NAD+ spray can replenish these levels in humans has no scientific proof behind it yet. Most of the studies refer to data obtained from animal studies or cell experiments only.
Weight-loss claims are the clearest example. They show up in marketing, and they are not backed by controlled human trials. If a seller leads with them, treat that as a warning sign. Our benefits page separates the lab findings from the sales copy.
On the 24th of August 2026, warning letters were dispatched by the FDA to five companies dealing with peptides online, for selling new substances that were not authorized. NAD+, however, was absent on this occasion. Nevertheless, this logic stands true for every vendor selling the NAD+ nasal sprays in question.
According to the FDA, a "For Research Use Only" sticker does not clarify matters. Instead, it considers the entire website. For instance, information about ailments, administration instructions, and reconstitution calculators is taken by the FDA as proof that the products were designed for human use. Hence, companies do not include instructions for use and quantities on their websites.
All NAD+ products featured here are not approved by the FDA. Arc-1 products are made against a prescription, which is a different and legal path than that of an approved medicine.
Start with the question you actually have, because the answer changes by product type. A few common ones:
One last point from the vendor-checking side. Real Peptides holds a 4.2 out of 5 Trustpilot score from 85 reviews in the last 12 months, and the complaints that do appear include leaking or under-filled liquid products. With a spray, inspect the fill and the seal on arrival and keep the COA that matches your lot. If you have a health question, talk to your doctor, not a vendor.